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Measurement of conifers needles surface by MR tomography
Hladík, Roman ; Kubásek, Radek (referee) ; Mikulka, Jan (advisor)
This bachelor thesis deals with the tomography based on magnetic resonance and evaluation of scanned images of conifers needles. At first, it is described the physical basis and methods of magnetic resonance scanning of objects. Another part is devoted to graphical preprocessing, which consist of noise suppression and image segmentation. After that there are described the design and algorithm for parameter estimation implemented to the application. The first experimental measurements were lightly discussed and evaluated in the last part of the work. In the last part there are discussed results of the experimental measurement. The attached documents contain the source code in Matlab language.
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Titaniun Dioxide - Phosphonate Assemblies as Medical Nanoprobes
Řehoř, Ivan ; Lukeš, Ivan (advisor) ; Lang, Kamil (referee) ; Peters, Joop (referee)
Titanium Dioxide - Phosphonate Assemblies as Medical Nanoprobes Ivan Řehoř PhD. Thesis Abstract: Multimodal imaging-therapeutic nanoprobe TiO2@RhdGd was prepared and successfully used for in- vitro and in-vivo cell tracking as well as for killing of cancer cells in-vitro. TiO2 nanoparticles, 12 nm in diameter, were used as a core for phosphonic acid modified functionalities, responsible for contrast in MRI and optical imaging. The phosphonic acid derivatives, used for surface modification, allows for grafting extraordinarily high loads of irreversibly adsorbed molecules of both types in one step. The prepared probe shows very high 1 H r1 relaxivity value as well as relaxivity density value, both crucial parameters for its use in MRI. The presence of fluorescent dye in its structure allows for its visualization by means of fluorescence microscopy. The applicability of the probe was studied, using three living systems - mesenchymal stem cells, cancer HeLa cells and T-lymphocytes. The probe did not exhibit toxicity in any of these systems and its long time storage in a lysosomal compartment was confirmed. Labeled cells were successfully visualized in-vitro by means of fluorescence microscopy and MRI. Consequent visualization of labeled cells in-vivo by means of fluorescence microscopy was also achieved....
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Automatic Producing of Cranial Implant Edge Surface
Hrdý, Libor ; Bartoň, Radek (referee) ; Kršek, Přemysl (advisor)
This thesis is focused to problems of automatic generation of border surface for cranial implant. This document includes description of 3D modeling human tissue, followed with issue of cranial implant. Next it includes possible perspectives of solving automatic generation problems for implant border. Second half of this document is focused to implementation of tool for automatic generation of border surface. Final part deals with results of work with this tool.
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Measurement of conifers needles surface by MR tomography
Hladík, Roman ; Kubásek, Radek (referee) ; Mikulka, Jan (advisor)
This bachelor thesis deals with the tomography based on magnetic resonance and evaluation of scanned images of conifers needles. At first, it is described the physical basis and methods of magnetic resonance scanning of objects. Another part is devoted to graphical preprocessing, which consist of noise suppression and image segmentation. After that there are described the design and algorithm for parameter estimation implemented to the application. The first experimental measurements were lightly discussed and evaluated in the last part of the work. In the last part there are discussed results of the experimental measurement. The attached documents contain the source code in Matlab language.
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